CD19 抗体
Quick Overview for CD19 抗体 (ABIN933901)
抗原
See all CD19 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein A affinity chromatography
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免疫原
- CD19 antibody (Azide free) was raised in rat using murine CD19-expressing K562 human erythroleukemia cells as the immunogen.
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亚型
- IgG2a
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应用备注
- Optimal conditions should be determined byt he investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Supplied as a liquid in PBS.
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储存液
- Without preservative
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- -20 °C
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储存方法
- Aliquot and store at -20 °C.
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- CD19 (CD19 Molecule (CD19))
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别名
- CD19
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背景
- B-lymphocyte antigen CD19 also known as CD19 (Cluster of Differentiation 19), is a protein that in humans is encoded by the CD19 gene. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase. . Synonyms: Monoclonal CD19 antibody, Anti-CD19 antibody.
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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